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Finally, the diet's fat-heavy aspect can have negative health consequences if dieters load up on too many trans and saturated fats, something that Wallace says is easy to do.

"People will go to McDonald's and get a triple cheeseburger, take the bun off, and eat that," he says. It was only enough for a few small tests, but D’Agostino’s excitement grew with each one. Keto Advanced 1500 Price says he began going to the lab in the middle of the night just to see how his rats were doing. The diester raised their ketone levels rapidly, regardless of what they were eating, and kept the levels unusually high for hours. When D’Agostino first began looking into synthetic ketones, other researchers had already synthesized a ketone molecule, known as a monoester, with funding from the U.S. military.

People following a keto diet are putting themselves at higher risk of the ‘silent killer’ non-alcoholic fatty liver disease , according to nutrition experts. By limiting the amount of carbohydrates and protein metabolized, energy is instead derived from fat within the body or consumed in the diet. As glucose levels decrease, fat-derived ketone bodies begin to take over as the body's main energy source, a metabolic state known as ketosis. In addition to weight loss, studies show that the ketogenic diet may also be helpful in treating many other conditions, such as type 2 diabetes, polycystic ovary syndrome , acne and more.

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